Artecoll consists of homegeneous polymethylmethacrylate (PMMA) microspheres, evenly suspended in a solution of partly denatured 3.5% collagen. All microspheres are in a range of 32-40 microns in size, are completely round and have polymerized, smooth surfaces. 99.9% of the remaining monomers have been removed during the processing of the PMMA. Artecoll contains an average concentration of 0.3% lidocaine hydrochloride. It is used as an injectable micro-implant for long-lasting subdermal augmentation, which includes the correction of wrinkles and of other defects in the connective tissue.